World Osteoporosis Day 20 October 2021: Take Action for Bone Health



World Osteoporosis Day is observed annually on 20 October, and launches a year-long campaign dedicated to raising global awareness of the prevention, diagnosis and treatment of osteoporosis and metabolic bone disease. We should insist on early prevention from lifestyle, and middle-aged and elderly people should be diagnosed and treated early. Pain, hunchback, reduced height and fractures are characteristic manifestations of osteoporosis, but there are many patients with osteoporosis who often have no obvious sensation in the early stages of the disease. Fractures are a direct consequence of osteoporosis, affecting the function of the body in mild cases and causing disability or even death in severe cases, with common fracture sites being the thoracolumbar spine, hip and arm. 

Osteoporosis is a chronic disease that can be prevented and treated. The first step is to have a balanced diet, increase the intake of calcium and moderate amount of protein in the diet, and have a low salt diet. Calcium intake has an irreplaceable role in the prevention of osteoporosis. Smoking, alcoholism, excessive intake of caffeine and carbonated beverages can increase the risk of osteoporosis. The next step is to exercise in moderation. Exercise can make bones stronger and also help to enhance the body's responsiveness, improve balance and reduce the risk of falls. The middle-aged and elderly population also need proper physical exercise, which helps improve muscle strength and osteoporosis prevention. Furthermore, it is necessary to increase sunlight exposure. Diet contains limited amount of vitamin D. Regular exposure to sunlight plays a key role in vitamin D production and calcium absorption. Experts recommend that the average normal person needs at least 20 minutes of sunlight per day. 

It is never too late to start treatment for osteoporosis at any stage as opposed to no treatment, but early diagnosis and early treatment will greatly benefit. People at risk should go to a regular hospital for osteoporosis testing and diagnosis and treatment as early as possible. It is reported that serum 25OH-vitamin D was lower than 50 nmol/L in 28.4% of the postmenopausal women, and this was associated with a relatively higher serum parathyroid hormone (PTH). Low levels of serum 25OH-vitamin D (<25 nmol/L) were most frequent in some countries of central and southern Europe. Treatment with vitamin D3 and calcium increased serum 25OH-vitamin D and decreased serum PTH significantly, and the effect was greater for lower baseline serum 25OH-vitamin D[1]. Vitamin D enhances intestinal absorption of calcium and phosphate. Low concentrations of vitamin D are associated with impaired calcium absorption, a negative calcium balance, and a compensatory rise in PTH, which results in excessive bone resorption[2]. PTH levels and 25 (OH) vitamin D levels can predict the rate of bone loss in the elderly. YHLO provides osteoporosis screening on Chemiluminescence (CLIA) platform for early diagnosis and timely treatment to prevent fracture risks.

[1] Lips P, Duong T U, Oleksik A, et al. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial[J]. The Journal of Clinical Endocrinology & Metabolism, 2001, 86(3): 1212-1221.
[2] Rosen H N, Rosen C J, Schmader K E, et al. Calcium and vitamin D supplementation in osteoporosis[J]. UpToDate, Waltham, MA.[Accés: 15 de juliol de 2014], 2017.



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